Syphilis has not gone
away, and in some places it is on the rise. During the 16th
and 17th centuries, there was a rebirth of humanism and the arts
which engulfed Europe. It was accompanied by a loosening of sexual restrictions
which had previously been observed. The
Protestant Reformation, led by Martin Luther, John Calvin, and others,
generally advocated less negative attitudes toward sexual matters than the
Catholic Church did. For example, although Luther was hardly liberal in his
sexual attitudes, he thought that sex was not inherently sinful and that
chastity and celibacy were not signs of virtue. At the same time, Europe was
caught in a massive epidemic of syphilis – which might have worked to limit
sexual freedom.
Syphilis is a
spiral-shaped microorganism, Treponema
pallidum, discovered in 1905.
This photomicrograph of
Treponema pallidum bacteria was taken from a tissue section. From
Hardin Library for the Health Sciences, University of Iowa.
Syphilis is usually transmitted by sexual
contacts, but it can also be acquired from blood transfusion or transmitted
from a pregnant mother to the fetus.
The earliest sign of
syphilis in its primary stage is a
sore called a chancre (pronounced “shanker”). The chancre generally appears two
to four weeks after infection. The most common locations for the chancre in 75
percent of cases, are the genitals and anus, but it can also develop on the
lips, in the mouth, on a finger, on a breast, or on any part of the body where
the bacteria can enter the skin. The
chancre begins as a dull-red spot which develops into a pimple. The pimple
ulcerates, forming a round or oval sore usually surrounded by a red rim. The
chancre usually heals within four to six weeks, leading to the erroneous belief
that the “problem” went away.
Primary
stage chancre
Secondary
syphilis is rare because it is mostly prevented by early
medical intervention. The second stage
without treatment, begins anywhere from one week to six months after the
chancre heals. The symptoms include a pale red or pinkish rash often found on
the palms and soles, fever, sore throat, headaches, joint pains, poor appetite,
weight loss, and hair loss. Moist sores called condyloma lata may appear around the genitals or anus and are
highly infectious. The symptoms of this secondary stage of syphilis usually
last three to six months but can come and go periodically. After all the
symptoms disappear, the disease passes into a latent stage. At this stage the
disease is no longer contagious, but the infecting microorganisms burrow their
way into various tissues, such as the brain, spinal cord, blood vessels, and
bones. Fifty to 70 percent of people with untreated syphilis stay in this stage
for the rest of their lives. The remainder, pass on to the late syphilis stage. It involves serious heart problems, eye
problems, and brain or spinal cord damage. These complications can cause paralysis,
insanity, blindness, and death.
Syphilis is usually
diagnosed by a blood test. Although tests are not completely fool-proof in
detecting the primary stage of syphilis, secondary syphilis can be diagnosed
with 100 percent accuracy. Diagnosis also depends on a carefully performed
physical examination looking for signs of primary or secondary syphilis.
Chancre sores can be observed on male sex organs, and chancres of the cervix or
vagina may be detected only by a pelvic examination. Examination of the fluid
taken from a chancre under a special microscope will usually show the
characteristic spiral-shaped organism.
Syphilis can easily be
treated with one injection in its primary and secondary stages. Later stages of
syphilis require treatment over a longer period of time, but the treatment is
usually successful.
Persons who have been
sexually exposed to someone with proven early syphilis should promptly seek
medical help.